PD :: Volume #4

#347: BOLD-FMRI

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zi zi, the inspection bed carries over the ring magnet, Gu Jun is motionless, is relaxing the mind, anything does not think, making the equipment first pat his comparison condition. 嗞嗞,检查床移向圆环磁体,顾俊一动不动,放松着头脑,什么都不想,让设备先拍下他的对照状态。 fmri machine revolution at the same time, in front of operation element stage of room, Professor horse and Shen Dr. and the others is watching the image pictures in several computer screens. fmri机运转的同时,设在前室的操作工作台前面,马教授、沈博士等人都在看着几块电脑屏幕中的影像图片。 At this time the blood stream quantity of Gu Jun brain demonstrates in the image, but only the professional can understand the different colors and color brilliance in this different brain area is what signal meaning, information that as well as these mr values, te values, t2 value and other parameters disclosed. 此时顾俊脑部的血流量就显示在影像中,但只有专业人士才看得懂这不同脑区的不同颜色和色彩明度是什么信号意思,以及那些mr值、te值、t2值等参数透露的信息。 Let alone Wu Shiyu, Cai Zixuan can only look at the chart to sigh similarly. 别说吴时雨了,蔡子轩同样只能望图兴叹。 „A'Jun this condition is normal.” Dr. Shen said the sentence to them. “阿俊这个状态是正常的。”沈博士跟他们说了句。 After a while, after input enough many comparison condition image data, Professor horse said to Gu Jun through the loudspeaker of inspection room: „A'Jun, then does to stimulate mission, rises from light to heavy. First I will mention the noun of unusual thing, you are listening carefully. If you have, do not endure, makes us know your situation with the cry the weight, if you could not endure, must ask me to stop immediately.” 过了一会儿,录入足够多的对照状态影像数据后,马教授就通过检查室的喇叭对顾俊道:“阿俊,接下来做刺激任务,从轻到重升上去。首先我会讲出异常事物的名词,你仔细听着。如果你感到头痛,不要忍着,用叫声让我们知道你情况的轻重,如果你忍受不了,一定要叫我马上停下来。” „Good.” Inspected Gu Jun in room to comply with the sound, „Professor horse, you started.” “好。”检查室里的顾俊应了声,“马教授,你开始吧。” horse teaches the calm middle-aged facial features, is ready in full battle array starts to say names slowly: „Incantation technique, deep submergence, different banyan tree sickness, human body different banyan fig......” 马教授沉着中年面容,严阵以待地开始慢慢说出一个一个名称:“咒术,深潜者,异榕病,人体异榕树……” The speech sound that as horse teaches, screen the color brilliance of brain image enhances immediately, the neuron activity of Gu Jun brain was more active. 随着马教授的话声,屏幕中的大脑影像的色彩明度顿时提高起来,顾俊脑部的神经元活动更活跃了。 „Different scale sickness, the ceremony, Dagon, Tian Yiqing......” Professor horse more said that image color is brighter, but the mood of people is also intense. “异鳞病,仪式,大衮,田意晴……”马教授越说,那影像色彩就越亮,而众人的心情也越是紧张。 „!” Gu Jun exuded the painful cry suddenly, he felt that in the head becomes an intermittent severe pain from the one's secret worries, has made his body start a little strongly straight. “啊！”顾俊突然发出了痛叫声,他感到脑袋里从隐痛变为一阵阵的剧痛,已让他的身体开始有点强直。 This was his stress condition, was the mission condition of this inspection. The computer through subtracts the comparison condition blood flow diagram the blood flow diagram of mission condition, may discover and in the mission condition the unique psychological operation related brain spot, but now in the screen is demonstrating the immediate contrast result together. 这就是他的应激状态了,也是这个检查的任务状态。电脑通过把任务状态的血流图减去对照状态的血流图,就有可能发现与任务状态中特有的心理操作有关的脑部位,而现在一块屏幕中就显示着即时对比结果。 Dr. Shen naturally can understand the image, when next looked is wrinkling the brow, two people said to Wu Shiyu in a soft voice: „First temporal lobe, amygdala and hippocampus, the blood stream quantities of these three places increased markedly.” 沈博士自然是看得懂影像的,当下一看就皱着了眉头,对吴时雨两人轻声道:“前额叶、杏仁核、海马体,这三个地方的血流量都显著增加了。” Cai Zixuan sighed immediately, grasps sends the bare forehead, was these three places is not the good deed...... 蔡子轩顿时不禁一叹,抓了抓发秃的额头,是这三个地方就不是好事…… He has read some ptsd research literatures, the ptsd brain imaging diagnosis had main research results is found that hippocampal parahippocampal gyrus, amygdala , the former temporal lobe patient had the function to be unusual, therefore before there are „, Temporal lobe amygdala” hippocampal loop this pathology hypothesis. 他有看过些ptsd的研究文献了,ptsd的脑影像学有一个主要研究成果就是发现患者的海马及海马旁回、杏仁核、前额叶等存在功能异常,所以有“前额叶-杏仁核-海马环路”这个病理假说。 Is the former temporal lobe is damaged to cause the function to weaken, thus to the adjustment and control action of amygdala weakens, making amygdala excessively strengthen to the terrifying natural response, but seahorse's harm as well as with being out of balance that the first temporal lobe and amygdala relate, participates to the harm process that the patient remembers. 即是前额叶受损导致功能减弱,从而对杏仁核的调节和控制作用减弱,使杏仁核对恐怖性反应过度增强,而海马本身的损害以及与前额叶、杏仁核之间联系的失调,也参与对患者记忆的损害过程。 Now the Tyrant Jun blood stream change measurement result, is conforming to the partial cerebral activity typical expression of this hypothesis. 现在壕俊的血流变化测量结果,符合着这种假说的局部脑活动典型表现。 But before Tyrant Jun , the before position of brain hemorrhage is the right temporal lobe, if before is that damage and related surgery cause , the temporal lobe function is unusual, this found the cause of disease. 而壕俊之前脑部出血的位置是右前额叶,如果是那次的损伤和相关手术导致前额叶功能异常,这就找到病因了。 „A'Jun, increases the stimulation now, you recalled that has matter on that island.” horse teaches also said that „, once cannot bear stops, reluctantly.” “阿俊,现在加大刺激,你回想一下发生在那个小岛上的事情。”马教授又说道,“一旦受不了就停下,不要勉强。” Gu Jun complied with is completing this to stimulate mission, the head was really painful his some is not soon able to endure, the breath became the respite. 顾俊遵从着完成了这个刺激任务,脑袋痛得他真有些快要无法忍受了,呼吸变为了喘息。 Then is mission of heaviest rank, gave him in fmri machine nearby nurse a document, is looks like the deep submergence body, the different banyan tree sickness patient and other pictures of unusual thing. Gu Jun only looked at 2-3, the head must have whole body muscle not independent twitch sign before the epileptic paroxysm on the severe pain, he closed the eye to stop immediately. 接着是最重级别的任务,在fmri机旁边的护士给了他一份文件,都是像深潜者尸体、异榕病患者等异常事物的图片。顾俊只看过了2-3张,脑袋就剧痛得出现了癫痫发作前的全身肌肉不自主抽动迹象,他顿时闭上眼睛停了下来。 But stimulation mission of this inspection also finished, but Gu Jun temporarily does not leave the inspection bed, making the machine continue to take down the brain blood flow change of his returning to normal process. 而这个检查的刺激任务也就此结束,但顾俊暂时不离开检查床,让机器继续录下他平复过程的脑部血流量变化。 Another side, Professor horse and Dr. Shen they look at the contrast image in computer, the complexion even more is ugly, a little surprised...... 另一边,马教授、沈博士他们看着电脑中的对比影像,面色都越发难看,也有点惊讶…… When Gu Jun recollection wound scene, the blood stream continues to increase ; When he watches the stress picture, he presents the hemodynamics drastic change, not only first temporal lobe, amygdala and hippocampus these three brain areas, but is the blood stream quantity of entire brain has the sharp increase, when this physiological reaction general ptsd patient stress is much more intense. 当顾俊回忆创伤性场景时,血流继续加大;而当他观看应激图片时,他出现血流动力学剧变,不只是前额叶、杏仁核和海马体这三个脑区,而是全脑的血流量都发生剧增,这种生理反应比一般ptsd患者应激时还要强烈得多。 Moreover such rapid entire cerebral hemorrhage is very dangerous, will cause the blood pressure on increase suddenly, is very easy to make in the brain the capillaries burst to cause to bleed. 而且这样迅速的全脑充血是非常危险的,会导致血压骤增,很容易使脑内微血管破裂而引起出血。 Considering that Gu Jun also has the cerebral hemorrhage medical history and opens the skull surgery history, the stress condition of this rank is sufficiently fatal to him. 考虑到顾俊还有脑出血病史和开颅手术史,这个级别的应激状态对他足以致命。 „It is not optimistic, really not optimistic......” Dr. Shen muttered, was not a pessimistic person, at this time felt at a loss. “不乐观,真的不乐观……”沈博士喃喃道,不是个悲观的人,这时却感到束手无策。 Gu Jun comes out after the inspection room, sees their facial expressions, knows that the situation is not optimistic. 顾俊从检查室出来后,一看到他们的神情,就知道情况不乐观了。 When he looked at these image results, the heart is somewhat vacant, the function that the first temporal lobe damage causes is unusual, this was very difficult to govern...... 当他看了那些影像结果,心头有些茫然,前额叶损伤导致的功能异常吗,这就很难治了啊…… „Salty handsome.” Wu Shiyu patted his shoulder, „before over half a month, your also stupor, slowly good.” “咸俊。”吴时雨拍了拍他肩膀,“大半个月前你还昏迷着呢,慢慢会好的吧。” „Un.” Gu Jun nods to her, teaches to say to horse: „Professor horse, I wants also to make mri and mrs these, investigates thoroughly.” “嗯。”顾俊对她点点头,又向马教授道:“马教授,我想把mri、mrs那些也做了,查清楚点。” mri is the nuclear magnetic resonance, uses is the brain morphometry in the brain function inspection, mrs is in vivo spectroscopy surveying, can survey the volume of seahorse, appraises the seahorse neuron to lose or harm. Because the change of formatio hippocampi is the typical symptom of ptsd patient. mri是核磁共振,用在脑功能检查上属于脑形态测量学,mrs则属于活体磁共振波谱测量学,都能测量海马的体积,评估海马神经元有没有丢失或损害。因为海马结构的改变是ptsd患者的典型症状。 Makes these two inspections to need first to hit the emission active material, is the contrast medium, before caused the vice- use easily not to use to his body because of the worry. 做这两种检查都需要先打放射活性物质,也就是造影剂,之前因顾虑对他身体造成副使用不轻易使用。 The present is not only the Gu Jun request, is bold-fmri is unable to indicate its hippocampus structure situation, after Professor horse and Dr. Shen one discussed that agreed to inspect, but first made Gu Jun rest for three hours in the laboratory. Then the nurse called the contrast medium him, then he successively completed mri and mrs inspection. 现在既是顾俊要求,又是bold-fmri无法表明其海马体的结构情况,马教授和沈博士一番商量后,同意进行检查,但先让顾俊在实验室里休息了三个小时。然后护士给他打了造影剂,接着他先后完成mri和mrs检查。 mri assumes the dissection image, but mrs is the record is measured in the individual the syntheses of all chemistry signals, the measurement result is by the spectrograms of many spectral lines. mri是呈解剖图像,而mrs是纪录被测个体中所有化学信号的综合,测量结果是由多条谱线的谱图。 But in the Gu Jun mri image has hippocampus to accumulate indirect sign of reduction- his lateral ventricle temple corner/horn expands, the seahorse head gutter vanishes. 而顾俊的mri影像上有海马体积缩小的间接征象-他的侧脑室颞角扩大,海马头部浅沟消失。 the mrs result also showed that signal that his seahorse neuron number has the reduction. mrs结果也表明,他的海马神经元数目有减少的信号。 On this day, Gu Jun also made other inspections, for example draws blood to measure the bdnf level( brain source nerve trophic factors), the bdnf level of ptsd patient usually is lower than the normal crowd. But now his bdnf level is somewhat low , compared with the result of previous physical examination falls sharply. 在这一天,顾俊还做了一些其它检查,比如抽血测bdnf水平(脑源性神经营养因子),ptsd患者的bdnf水平通常低于正常人群。而现在他的bdnf水平就偏低了,与上一次体检的结果相比更是大幅下跌。 The secret bureau has the study data to indicate that the bdnf level of high spiritual awareness crowd will be higher than the normal crowd, this also possibly is its spirit knowledge origin. 天机局有研究数据表明高灵知人群的bdnf水平会比正常人群高,这也可能是其灵知来源。 Now Gu Jun as if not only loses his high spiritual awareness, but also had the neuroendocrine characteristics of ptsd pathology. 现在顾俊似乎不但是失去他的高灵知,而且有了ptsd病理的神经内分泌特征。 All these check results are placed in the same place, Professor horse they knows that the answer was anything...... the Gu Jun brain shape really has the change. 所有这些检查结果摆在一起,马教授他们都知道答案是什么……顾俊的大脑形态确实有改变了。 „A'Jun, you first go back to rest well, relax, do not think so many, we will discuss that is most suitable your therapeutic schedule.” Dr. Shen thought of comforts to say with ease, sent out the laboratory the Gu Jun three people. “阿俊,你先回去好好休息,放松心情,不要想那么多,我们会商讨一个最适合你的治疗方案的。”沈博士装着轻松地安慰说,把顾俊三人送出了实验室。 Then, Dr. Shen and Professor horse arrive around conference room open far regulation conference, Master Tong and Yao Shinian, have chief and the others, is waiting for this report of examination. 接着,沈博士和马教授来到旁边的会议室开远程会议,通爷、姚世年、还有局长等人,都在等着这份检查报告。 The robot tile strength said 机器人瓦力说 First, asked the monthly ticket, sought the subscription! 第一更,求月票,求订阅！
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