The chaptermistake, thisreporting( exemptsregistration), such asmeets the contentadditive devicewrong characterorderto be chaotic, pleasewithdraw from the readingpatternorreads the patternto be then normalsmoothly.
章节错误,点此举报(免注册),如遇到内容乱码错字顺序乱,请退出阅读模式或畅读模式即可正常。Another side, afterremovingcompletebarrier, the zerostageresearch and development effort of immunityreconstructiontherapycame to an endfinally.
另一边,在扫除全部障碍之后,免疫重建疗法的零阶段研发工作终于宣告结束。
……
……Yes, does not start, butfinished.
是的,并不是开始,而是结束。In fact, the technicaldocuments that afterattainingYe Zhouprovides, a research team of the domestictopclinicalexperthad been reassigned, buttheirduties are also very simple, thatis100defers to the technical manual, completes the reappearance of firstcase of immunityreconstructiontherapyin the laboratory.
实际上,在拿到叶舟提供的技术文档之后,一只由国内顶级临床专家组成的攻关小组就已经被抽调出来,而他们的任务也很简单,那就是100按照技术手册,在实验室中完成第一例免疫重建疗法的复现。Now, theyhave completed the completemouseexperiment, is revolvingbefore the report of latest output, discussionactualcurative effectandhuman bodysecureresult.
现在,他们已经完成了全部的小鼠实验,正围绕在最新输出的报告前,讨论实际的疗效和人体安全性结果。
„ Before clinical of B-NDGmouse , did the modelcome out? Finallyhow? „
“B-NDG小鼠的临床前模型出来了吗?结果怎么样?“Whatinquirysits a white hairold maninmost, nameddeclaresto become, is the domesticimmunityreconstructiontherapydomainsenior statesman, oncemade the great contributionin the PBMCtherapy.
提问的是坐在最中间的一名白发老者,名叫宣成,是国内免疫重建疗法领域的元老,曾经在PBMC疗法上做出巨大贡献。„Basicallyhad come out, from the currentresult, the survival percentage of thisbatch of micehas achieved100, but the life cyclehas the fluctuation, acceptssome time after experiment, over 20micepresented the obviousbody weightto reduce.”
“基本上已经出来了,从目前的结果来看,这批小鼠的存活率都已经达到了100,但是生存周期存在波动,接受实验后的一段时间里,有20以上的小鼠出现了明显的体重减少。”
„ Meanwhile, wealsoobserve the phenomenon that some experimentbodieshadmanic, hadanxiouslyandevenbite. „
“同时,我们还观察到了少部分实验体出现了狂躁、焦虑、甚至有自咬的现象。“„Control experimenthas been conducted many are times, made the adjustmentincluding the PBMCdosage and therapy, butis very strange, thisissueexists.”
“对照实验已经进行过很多次了,包括PBMC的剂量和疗法都做了调整,但是很奇怪,这个问题还是存在。”The one whorepliedwasteam leaderforestcelebrate of zerophasegroup, onhisfacewrote all over the doubts, as ifcould not feel the mindtothisresultcompletely.
答话的是零阶段工作组的组长林庆,他的脸上写满了疑惑,似乎对这个结果完全摸不着头脑。In fact, ifstandshisangle, thisissuetrulylooked likehitsequallyweirdlycleverly.
事实上,如果站在他的角度上来看,这个问题确实就像是撞鬼了一样邪门。Allcanadjust the variable and controllingto adjust, allartificialor the non-artificialperturbationhad removed, eventheirtesting cabintradedseveral, but the mouse of this/shouldoutbreakis taken bad.
所有能够调整和控制的变量都已经调整了,所有人为或者非人为的扰动都已经排除了,甚至他们连实验舱都换了好几个,但该发病的小鼠还是发病。
……
……Orthatcannotbe called the outbreak, because the mousehas not displayed the obviousmorbid statecharacter, symptomalsoallnormal, ifaccording to the requirements of othernon-coreexperiment, thisevencanbe regarded the right and wrongessentialfactorslightlyto cross.
或者说那也不能叫做发病,因为小鼠并没有表现出明显的病态性状,体征也一切正常,如果按照其他非核心实验的要求,这甚至可以被当成是非关键因子略过了。After all, the mousegoes crazyto havemanyreasons, may bebecause of the temperature change, being possible bebecause the airis too dry, evenmay bebecausestepped onstatic electricityaccidentally......
毕竟,老鼠发疯有很多原因,有可能是因为温度变化,有可能是因为空气太干燥,甚至有可能是因为偶然踩上了一次静电……However, insuchproject, hedoes not have the meansto ignoretoanysmallunusuality, becausethisstagetheyare not exploringnow, butis duplicating.
但是,在这样的项目里,他没办法对任何一点微小的异常置之不理,因为现在这个阶段他们不是在探索,只是在复制。
Can the firstfoundationtheorem that hecandeterminemake a mistakewithitsquestiontechnologydocuments, might as wellinspect the implementationagain.
他能确定的第一条基础定理就是与其质疑技术文档会不会出错,不如再重新检查执行过程。Therefore, based onthisjudgment, theyeventraded the fresh air handling system in laboratory, butstillhad not actually solvedto accept the issue that the mouse after treatmentgoes crazyregularly.
所以,基于这个判断,他们甚至把实验室里的新风系统都换了,但却仍然没有解决接受治疗后的小鼠隔三差五发疯的问题。
„ CanbeGVHDissue that because the highproportionpersonimmune cellcauses? „
“会不会是因为高比例人免疫细胞引起的GVHD问题?“declaresto becomeis frowningto ask.
宣成皱着眉头问道。So-calledGVHDis the transplantanti-hostsickness of popular name, inanyinvolvesin the PBMCimmunityreconstructiontherapy to appear.
所谓的GVHD就是俗称的移植物抗宿主病,在任何涉及到PBMC的免疫重建疗法中都有可能出现。„, Wewill not have attemptedto adjustmanyare inferior, had removedmostvariables, determined that is notGVHDcauses.”
“不会,我们已经尝试调整过很多次了,已经排除了大部分的变量,确定不是GVHD导致的。”
” Operational procedure? Hasnon-standardmovement that the human factorcauses? ”
”操作流程呢?有没有人为因素导致的非标准动作?”„No, wemissed a placeplaybackingvideo recording.”
“没有,我们就差一帧一帧地回放录像了。”forestcelebratesighed, shruggedreluctantly.
林庆叹了口气,无奈地摊了摊手。Hearsthissaying, the people in conference roomare silent, theyknow the zerostageexperiment of thisprojectimportantly.
听到这话,会议室里的众人都沉默下来,他们都知道这个项目的零阶段实验有多重要。Not is only because the laboratoryresultwill be appliedtoa group ofcritically illimmunityclassdisease patientsonurgently, savesthemto remain not manylives.
不仅仅是因为实验室结果将会被紧急应用到一批重症免疫类疾病患者身上,挽救他们所剩不多的生命。
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